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Tennessee Authorities Investigate Drug Mix-Up at Nashville Hospital

Tennessee authorities are investigating after four patients at Ascension Saint Thomas Midtown received potassium instead of pain medication during surgery.

Published August 20, 2026 at 4:05 PM EDT

The short answer

Tennessee authorities are investigating after four patients at Ascension Saint Thomas Midtown received potassium instead of pain medication during surgery. Tennessee authorities and the Tennessee Bureau of Investigation are looking into a medication error that affected four patients at Ascension Saint Thomas Midtown in Nashville.

Tennessee Authorities Investigate Drug Mix-Up at Nashville Hospital

The Facts

Who
Four patients, hospital CEO Dr. Shubhada Jagasia, and the Tennessee Bureau of Investigation.
What
A medication error involving four patients receiving potassium instead of pain drugs.
When
Friday, Aug. 14
Where
Ascension Saint Thomas Midtown in Nashville, Tennessee
Why
Four patients experienced complications after being administered the wrong medication during routine surgeries, leading to a state investigation and new hospital safety protocols.

Tennessee authorities and the Tennessee Bureau of Investigation are looking into a medication error that affected four patients at Ascension Saint Thomas Midtown in Nashville. On Friday, Aug. 14, four individuals undergoing routine joint replacement surgeries received doses of potassium instead of the intended pain medication.

The hospital facility, which identified the incident on the day it occurred, reported that the surgeries were originally scheduled as outpatient procedures. Hospital officials confirmed that the patients experienced complications following the drug mix-up, and staff have since met with the families of those affected.

Dr. Shubhada Jagasia, the president and CEO of Ascension Saint Thomas Midtown, stated that the hospital self-reported the event to state regulators and initiated an internal investigation. While the hospital has not disclosed the specific cause of the error or the clinical details of the patients, Jagasia noted that corrective safeguards and enhanced safety protocols have been implemented at the facility.

The Tennessee Bureau of Investigation was alerted to the matter by the Tennessee Healthcare Facilities Commission. The investigation remains active to determine how the medications were mixed up. Potassium is an electrolyte used in various medical treatments, such as for kidney stones or heart function, but high doses of potassium chloride are also utilized in executions.

The scale of this event involves four specific patients at a single major Nashville facility, but the regulatory response involves two state-level agencies: the Tennessee Healthcare Facilities Commission and the Tennessee Bureau of Investigation. For the thousands of patients who utilize Ascension Saint Thomas Midtown for surgeries, the implementation of "enhanced safety protocols" represents a concrete change in how clinical teams will handle and verify medications moving forward. While the hospital has not publicized the exact nature of these safeguards, patients may notice more rigorous double-checks or new pharmacy verification steps during the pre-operative and operative phases of their treatment to prevent similar electrolyte mix-ups.

The investigation sets a precedent for how Tennessee regulators and law enforcement respond to self-reported clinical "events" involving high-risk medications. Because potassium chloride can be lethal in incorrect doses, the involvement of the Tennessee Bureau of Investigation indicates that the state is treating the administration of incorrect drugs as a matter requiring formal law enforcement oversight rather than just internal hospital review. What happens next depends on the findings of the state investigation and the Tennessee Healthcare Facilities Commission's review of the hospital’s new safety protocols. Further details regarding the cause of the mix-up or potential legal actions have not yet been reported.

Summaries are written by The Plain Record to state the facts of a story plainly and without political slant. See our editorial standards, or report a correction.

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Questions readers ask

What happened: Tennessee Authorities Investigate Drug Mix-Up at Nashville Hospital?

A medication error involving four patients receiving potassium instead of pain drugs.

Who is involved?

Four patients, hospital CEO Dr. Shubhada Jagasia, and the Tennessee Bureau of Investigation.

When did this happen?

Friday, Aug. 14

Where did this happen?

Ascension Saint Thomas Midtown in Nashville, Tennessee

Why does this matter?

Four patients experienced complications after being administered the wrong medication during routine surgeries, leading to a state investigation and new hospital safety protocols.